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TAKING YOUR HEALTH TO HEART
Cardiovascular disease is the leading killer worldwide. Although
the medical community, including the pharmaceutical industry, has made
great strides in developing treatments for a broad range of cardiovascular
disorders, we still have a long way to go. To this day, no adequate
treatment exists for acute stroke, which kills millions and leaves many
more paralyzed each year. Likewise, we're still in search of a long-term
therapy for congestive heart failure (CHF), which takes the lives of 50
percent of patients within 5 years of diagnosis.
But good news abounds. Management of high blood pressure, a key risk
factor for stroke and CHF, is now easier given the extensive number of
available medications used to create individualized therapy for each patient.
For some conditions, such as coronary artery disease (CAD), surgery can be
replaced by drug therapy. When operations are still required, new techniques
enable higher survival rates and faster recuperation so that patients can
return to normal lifestyles within a few weeks. Research into risk factors
has spawned massive educational efforts that have successfully encouraged
people to smoke less, reduce fat in their diets, and exercise more -- key
components of heart-healthy lifestyles.
Searle is well-positioned at the forefront of cardiovascular medicine.
We've made important contributions
to the treatment of hypertension, CHF, CAD and arrhythmia. We're also well
into the development of new medications
for stroke and other conditions, and continue to improve our existing product
lines in innovative ways. For example, we are pioneers in
offering a new formulation that enables people with heart disease to take
medication that reaches maximum concentration at the time of day
when blood pressure and heart rate are typically at their fastest rate of
Heart disease refers to several conditions that affect the heart; these include congenital heart defects, arrhythmias (heart rhythm problems), coronary artery disease and blood vessel diseases. Cardiovascular disease refers to conditions that cause blocked or narrowed blood vessels which can lead to stroke, angina (chest pain) or heart attack. Heart disease and Cardiovascular disease are often used interchangeably. The majority of heart diseases can be treated or prevented with lifestyle changes such as diet and exercise.
Heart disease symptoms will vary depending on the condition and whether the patient is male or female. For example, women are more likely to suffer from extreme tiredness, nausea, and shortness of breath, whereas men experience chest pains. However, in general, typical symptoms of heart disease include:
• Chest discomfort
• Chest pressure
• Chest tightness
• Chest pain
• Shortness of breath
• Numbness, pain or weakness in the parts of the body with narrowed blood vessels
• Pain in the back, upper abdomen, throat, jaw, and neck
Sufferers are not often diagnosed with cardiovascular disease until they have a stroke, heart attack or heart failure. Therefore, it is important to pay attention to any symptoms of cardiovascular disease and report them to a doctor immediately. Cardiovascular disease can be detected early and preventative measures taken with regular health check-ups.
Tribulus terrestris is commonly known for its men’s health and testosterone level benefits. However, it is also known to benefit the cardiovascular system. It is a small leafy plant native to the sub-Himalayan forests of Burma, India and several other countries. Traditional Chinese medicine has always used tribulus for its vasculature and heart benefits. But there are also several other tribulus terrestris health benefits Studies have found that due to its high level of antioxidants and its constituent tribulosin, it protects the body against reperfusion and ischemia-induced cardiac damage. It also increases free radical scavenging activity which protects against hypoxia-induced cell damage. Medical experts recommend taking between 85 to 250mg mixed in juice or milk three times per a day with meals.
Fortunately, heart and cardiovascular disease are preventable; there are several things one can do to prevent it. These include the following:
Exercise: Regular exercise will strengthen the heart and improve circulation. It also helps to reduce blood pressure and cholesterol and maintain a healthy weight.
Limit alcohol: Consuming a lot of alcohol will increase blood pressure. Alcohol is also high in calories which will lead to weight gain. High blood pressure and excess weight both increase the risk of heart disease.
No smoking: Smoking raises blood pressure and increases the risk of stroke and heart attack. People who smoke should stop, and those who don’t, shouldn’t start.
Stress reduction: Cortisol is referred to as the stress hormone, it Is released into the bloodstream when the body is under pressure. A small amount is healthy because it activates the fight or flight response to protect human beings from danger. However, too much cortisol as a result of constant stress and worry can lead to heart disease.
Heart health is essential to a long life; it is vital that one is consistent with a healthy diet and exercise as well as avoiding destructive lifestyle habits to avoid falling victim to heart disease.
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- Chronotherapy & Circadian Rhythm
Headlined "What Makes You Tick?" this site explains how the science of chronotherapeutics is being used to help persons with health conditions such as angina and allergies to match their medical therapy to their body clocks.
This site explains the eligibility criteria and sign-up procedures for the CONVINCE (Controlled ONset Verapamil INvestigiation of Cardiovascular Endpoints) trial. The study, involving about 15,000 patients, is designed to determine whether a new form of the hypertension drug verapamil is at least as effective as older treatments such as diuretics and beta blockers.
The sites listed below are not sponsored by Searle and their listing here does not reflect Searle
participation or endorsement. The listing is not all-inclusive but is provided as a guide to
some of the sites that have related information.
American Heart Association
The official site of the American Heart Association provides
information on how to prevent and treat heart disease, including a
test to measure visitors' personal risk profiles.
Sponsored by the Galichia Medical Group, this site offers a variety of
information resources on the prevention and treatment of heart
disease, including a list of frequently asked questions (with answers)
and the opportunity to submit your own question to one of its resident
Created by a physician who is also a heart patient, this site offers a
range of services -- including a glossary, a drug database, highlights
from the news, CPR instructions, articles on cardiovascular disease,
and the opportunity for registered "members" of the site to submit
- The Heart: An Online Exploration
Sponsored by the Franklin Institute, this site contains a comprehensive guide to facts about the heart. It includes movies and audio segments.
- Home Page of The Cardiovascular Institute of the South
Center for nonsurgical and surgical treatment of heart and vascular disease in an area that has one of the highest incidences of cardiovascular disease in the world.
- Home Page for Massachusetts General Hospital Neurosurgical Service
Helpful and comprehensive articles about prevention, diagnosis and treatment of hypertension, CHF, etc.
- What You Need to Know About Strokes
Facts on stroke from the Pharmaceutical Reseachers and Manufacturers of America (PhRMA).
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